Clinical Trials

The GW Medical Faculty Associates is proud of its physician scientists and their commitment to medical research. These clinical studies are designed to add to the medical knowledge base and relate to the treatment, diagnosis, and prevention of diseases or conditions.

To assess the role of administering TXA pre-cord clamp in three different routes of administration (IV push, IM and IV infusion) for preventing postpartum hemorrhage.

Obstetrics and Gynecology (OB/GYN)

We are trying to learn more about if the gut microbiome (the microbes that live in our digestive tract) of individuals with eAD, MCI, and healthy controls are altered following lifestyle changes.

Geriatrics and Palliative Medicine

GW joins a nationwide network of research centers in the Northeast ALS (NEALS) Consortium who are partnering with the Sean M HEALEY & AMG Center to conduct the first ALS platform trial. The platform trial is designed in a way that allows for testing multiple drugs simultaneously while reducing the amount of patients that receive placebo. The trail operates under a master protocol which…

Neurology and Rehabilitation Medicine

The purpose of the study is to assess the success of a single administration of Staccato alprazolam compared with placebo both in rapidly terminating a seizure episode within 90 seconds and with no recurrence of seizure(s) up to 2 hours after investigational medicinal product (IMP) administration.

Neurology and Rehabilitation Medicine

SATURN is a multi-center, pragmatic, prospective, randomized, open-label, and blinded end-point assessment (PROBE) clinical trial. A total of 1,456 patients presenting within 7 days of a spontaneous lobar ICH while taking statins will be randomized to one of two treatment strategies: discontinuation vs. continuation of statin therapy (using the same agent and dose that they were using at ICH…

Neurology and Rehabilitation Medicine

To assess the role of administering TXA pre-cord clamp in three different routes of administration (IV push, IM and IV infusion) for preventing postpartum hemorrhage.

Obstetrics and Gynecology (OB/GYN)

This study will include collecting blood samples to send to the lab on patients who are found to be at higher risk for transfusion using both inpatient nursing evaluation and validate our prediction model.

Obstetrics and Gynecology (OB/GYN)

The purpose of this study is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA (1) reduces recurrent stroke, acute coronary syndrome, and all-cause mortality 6 months after the event, and (2) improves stroke outcomes at 3 months in patients who experienced an ischemic stroke.

Neurology and Rehabilitation Medicine

This project is a prospective, observational study aimed to predict bleeding using hemoglobin trends measured non-invasively in patients undergoing elective cesarean delivery at the George Washington University Hospital.

Obstetrics and Gynecology (OB/GYN)

To develop maternal-fetal PBPK models for drugs commonly taken by pregnant women including Labetalol, Sertraline, Famotidine, and to validate these models with blood concentrations from maternal and umbilical cord blood samples.

Obstetrics and Gynecology (OB/GYN)

To evaluate the relative sensitivity and specificity of HPV methylation testing from self-collected compared to clinician-collected samples for detection of cervical precancer.

Obstetrics and Gynecology (OB/GYN)

The primary objective of the study is to assess the clinical utility of combining NIPT-based zygosity measurements with ultrasound chorionicity assessments for the management of twin pregnancies.

Obstetrics and Gynecology (OB/GYN)

Study RA101495-02.302 is a multicenter, open-label extension study to evaluate the long-term efficacy, safety, and tolerability of zilucoplan in subjects with gMG who have previously participated in a qualifying Ra Pharmaceuticals sponsored zilucoplan study.

Neurology and Rehabilitation Medicine